26/05/2026

Colmax: Natural Choline for Neural, Metabolic, and Digestive Well-being in Pets

In companion animal nutrition, well-being begins long before food reaches the bowl. Ingredient quality and nutrient balance are key factors in sustaining the vitality and metabolic health of dogs and cats.

Among these nutrients, choline plays a fundamental role. Its presence in the diet contributes to proper liver function, lipid transport, and the development of the nervous system. Dogs and cats do not synthesize sufficient amounts on their own, making the inclusion of this ingredient essential.

Colmax is a natural source of choline and inositol developed by Adinnova to help regulate liver, lipid, and energy metabolism. Its plant-based formulation enables this essential nutrient to be incorporated into different pet food formulations in a stable and safe manner.  
Why Is Choline Key in Pet Nutrition?
Choline is involved in fundamental physiological processes, particularly liver metabolism, fat transport, and nervous system function. When dietary intake is insufficient, liver disorders, reduced vitality, or muscle weakness may occur.

Traditionally, the most widely used source of choline in animal nutrition has been choline chloride. However, this molecule presents certain technological limitations. It is a hygroscopic and reactive compound that can interact with other dietary ingredients, affecting the stability of sensitive nutrients during feed processing and storage. Among the most common effects are the oxidation of vitamins, pigments, and amino acids. Moreover, its origin is associated with petrochemical byproducts.

Natural sources of choline represent an alternative aimed at overcoming these limitations. Plant-based choline is associated with phospholipids such as phosphatidylcholine, which are in the cellular membrane structure and contribute to its biological stability.
Adinnova's Natural Choline
Adinnova's source of choline and inositol, Colmax, was developed to contribute to metabolic balance in animal nutrition. Its formulation combines plant-based choline with functional compounds that support cellular performance.

Its components include phospholipids, such as phosphatidylcholine and phosphatidylinositol, as well as coadjuvants, for example, butyric acid and plant extracts, that support intestinal and liver health and nutrient absorption. This combination helps optimize lipid transport and utilization, helping metabolic balance and pet vitality through nutrition.

Another relevant characteristic is its technological stability. Colmax is a fluid, non-hygroscopic presentation that withstands the thermal treatments commonly used in pet food processing, as these molecules remain active and maintain absorption capacity. In turn, its use allows lower inclusion levels in the formula compared with synthetic choline sources, optimizing formulation efficiency and economic performance.
The Impact of Colmax in Pet Care
Colmax provides choline, a pseudovitamin that dogs and cats do not synthesize in sufficient amounts. Its presence in the diet helps reinforce the integrity of cell membranes and participate in neurometabolic processes linked to vitality and normal body function.

This nutritional additive supports the healthy development of the brain, heart, liver, muscles, and nervous system, contributing to the overall well-being of animals through nutrition.

Its stable formulation also allows easy incorporation into pet food. The recommended dosage in pet care ranges from 150 to 500 g/ton of feed, and it can replace choline chloride (60%) at an approximate ratio of 1-4, optimizing the use of space in the diet.

By supporting cellular function, Colmax helps sustain the vitality and well-being of dogs and cats throughout all life stages. Its nutritional contribution reinforces cell membrane integrity, supports neuronal development, and contributes to pets' overall health.
Studies on Colmax
This biosolution has been supported by scientific evaluations aimed at understanding its effect on animal metabolism. During 2024 and 2025, Adinnova carried out studies in collaboration with the National Institute of Agricultural Technology (INTA) to analyze productive, metabolic, and physiological parameters, including performance, liver function, and tissue analysis. The results validated the contribution of Colmax as a nutritional additive that supports the general well-being of animals.  
Gene expression studies were also conducted using advanced sequencing technologies to observe how the organism responds to its inclusion in the diet. Analyses have shown that Colmax modulates several metabolic pathways linked to nutrient utilization and cellular energy production.

Lower activation of genes associated with cell proliferation processes was observed. When dysregulated, these mechanisms are often linked to different pathologies, including tumor processes such as cancer. In other words, Colmax supports an active and balanced metabolism without stimulating cellular mechanisms associated with uncontrolled proliferation. By Adinnova
Source: All Pet Food Magazine

About Adinnova
Adinnova is an Argentine company, present in international markets, dedicated to the development of natural additives for animal nutrition. Each biosolution integrates science and innovation applied to wellbeing and productivity.

More information on our website: adinnova.com.ar