Sinergia and the Role of Probiotics in Supporting Digestive Health in Pets

After years of focusing solely on basic requirements, advancements in microbiology and functional nutrition have positioned intestinal health as a key pillar for animal well-being. Microbiota research has evolved beyond basic science and is now driving the development of value-added pet foods.

Today, pet food manufacturers, veterinarians, and pet owners recognize that the balance in the intestinal microbiota directly impacts digestion, nutrient use, immune response, and pets' quality of life. Thus, there is a transformation in food formulation and the development of functional ingredients.

Why is Microbiota Now a Key Factor in Pet Food?

The intestinal microbiota is composed of billions of microorganisms that interact continuously with the host. Far away from having a passive role, they participate in crucial digestive, metabolic, and immune functions.

A balanced microbiota is now known for its contributions to the integrity of the intestinal barrier, improved nutrient utilization, and the maintenance of physiological mechanisms associated with overall health. In other words, alterations in the microbiota's composition can negatively impact pets' well-being and digestive function.

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What is the Role of Probiotics Within This Nutritional Approach?

Probiotics are among the most relevant tools for supporting microbiota balance. Their function goes beyond incorporating live microorganisms into food: they create favorable conditions for the intestinal ecosystem and contribute to overall animal well-being.

Current research focuses on understanding which microorganisms are incorporated, the metabolites they produce, and their interactions with the resident microbiota. This different approach is becoming a key component in modern functional nutrition.

For manufacturers, this shift represents a concrete opportunity to develop science-based foods with differentiated characteristics that align with the increasing demand for products oriented toward digestive well-being and integral health.

What Characteristics Must a Probiotic Have to Provide Real Benefits in Pets?
 

Not all probiotics are equally functional. Efficacy depends on many factors, including strain selection, stability during production, and the ability to reach the gastrointestinal tract.
 

Marketplace

Colmax

FibiraPets

TanfolPets

Sinergia

SapNova

Natox

Hepatosafe

Adsor

In pet food, the primary technological challenge is ensuring microbial viability under severe conditions during extrusion and drying. This is why spore-forming microorganisms represent a major technological breakthrough. Endospores act as a natural protector against high temperatures, mechanical stress (pressure and shearing), and long periods of storage (shelf-life)—ensuring that the Colony-Forming Units (CFU) declared on the packaging remain viable until they reach the pet's bowl.

 'Sinergia by Adinnova is a solution developed to support the new generation of functional food oriented to the digestive well-being of dogs and cats'

In addition, strain selection must consider individual benefits, metabolite generation, and the interactions within the intestinal ecosystem.

How Was Sinergia Developed and What Market Needs Does It Address?

At Adinnova, we noticed a clear evolution in the pet food market's needs. Manufacturers look for solutions that differentiate their products through real functional benefits, supported by scientific evidence and compatible with modern industrial processes.

From our experience in applied microbiology and the development of biotechnological solutions for animal nutrition, we identified the need to address intestinal health from a broad perspective, considering not only microorganisms but also functional metabolites that participate in microbiota balance.

Sinergia by Adinnova was created under this vision—it is a solution designed to support the new generation of functional foods oriented toward the digestive well-being of dogs and cats.

Why is Sinergia Different from Other Available Solutions?

The main characteristic of Sinergia is its symbiotic ecosystem design. It is not formulated simply by different microorganisms but also a strategic consortium selected by its complementary mechanisms of action:
 

• Bacillus consortium (thermostability and digestibility): It is composed of Bacillus subtilis, Bacillus licheniformis, and Bacillus coagulans. In addition to their resistance to extrusion, these strains act as bio-factories in the intestine, producing extracellular enzymes (protease, amylase, and lipase) that maximize nutrient utilization. B. coagulans also contributes to lactic acid production, which is fundamental to the modulation of intestinal pH and competitive control of pathogens.
  
  

'More than an additive, Sinergia by Adinnova is a driver of functional metabolites designed to impact systemic health from the gastrointestinal tract'

• Clostridium butyricum (intestinal barrier integrity): It stands out for being the primary producer of butyric acid. This short-chain fatty acid is the main source of energy for colonocytes; thus, it is essential for maintaining the epithelia's tight junctions, preventing leaky gut syndrome, and modulating local inflammatory responses.
   
• Saccharomyces cerevisiae (probiotic immune modulation): As a live, biologically active probiotic yeast, it provides a differentiated cellular approach compared to bacteria in the formula. It promotes the digestive ecosystem's balance and stability, while its components within the cell wall—rich in glucans and mannooligosaccharides (MOS)—actively intercept pathogens by stimulating the Gut-Associated Lymphoid Tissue.
   

More than an additive, Sinergia by Adinnova is a driver of functional metabolites designed to impact systemic health from the gastrointestinal tract.

What Benefits Does Sinergia Offer to Food Manufacturers and to the Pets That Consume Those Products?

For manufacturers, Sinergia is an innovative tool grounded in applied microbiology, enabling the development of valuable solutions aligned with global trends in functional nutrition and intestinal health.
 

On the other hand, the goal is to support the balance of the microbiota in dogs and cats through microorganisms and functional metabolites that help maintain favorable conditions for digestive health and welfare.

The Future of Functional Nutrition

A deeper understanding of the gut microbiota is shaping the future of pet nutrition. Nutritional solutions are evolving from conventional formulations toward comprehensive strategies that harness the interactions among microorganisms, functional metabolites, and the host.
 

At Adinnova, we believe that the future of pet food will increasingly depend on a deep understanding of microbial ecosystems and the ability to translate knowledge into innovative solutions for the industry.

By Gonzalo Vicente MEng, R&D Director at Adinnova
Source: All Pet Food Magazine

About Adinnova
Adinnova is an Argentine company, present in international markets, dedicated to the development of natural additives for animal nutrition. Each bio-solution integrates science and innovation applied to wellbeing and productivity.
More information on our website: adinnova.com.ar