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Gut Helath: What Does Science Say About the Microbiome and the Role of Plasma in Pets?
Functional Additives

4+ MIN

Gut Helath: What Does Science Say About the Microbiome and the Role of Plasma in Pets?

Today, the intestine is recognized as a key axis connecting digestion, immunity, and overall well-being. As a result, the microbiome has become one of the main drivers of innovation in animal nutrition.
  At APC, this focus on gut health is not a recent trend but rather the natural evolution of decades of research in nutrition. The company specializes in functional ingredients for animal nutrition and began its work with plasma-derived functional proteins in livestock production, where the link between gut integrity, immunity, and performance is well documented. Over time, this expertise has been transferred to the pet food sector, where the microbiome is now understood as a crucial factor in improving quality of life for dogs and cats, even in apparently healthy animals.
  The intestinal microbiome plays a key role in digestive, immune, and metabolic health, directly impacting overall well-being.  
The Gut: A Key Ecosystem for Whole-Body Health
The gut is not just a digestive organ. It is a complex ecosystem where nutrients, microbiota, and the immune system interact continuously. A significant portion of the body's immune defenses is located in the intestine. Therefore, any imbalance in the microbiota can have effects that extend well beyond digestion.
  Disruptions in this ecosystem are associated with recurring digestive disorders, poor stool quality, or food intolerances. Moreover, they are linked to inflammatory processes that may affect skin condition, immune responsiveness, and overall metabolism. Increasing scientific evidence confirms that maintaining a balanced microbiome is essential for long-term systemic stability.   Plasma: A Functional Protein with Benefits Beyond Nutrition
Within this context, plasma has established itself as a high-value functional ingredient. It is a nutrient-dense protein obtained from surplus blood collected at facilities approved for human consumption. Through a carefully controlled spray dried process, its functional components are preserved.
  Unlike many conventional protein sources used in pet nutrition, plasma provides not only amino acids but also bioactive compounds such as immunoglobulins, growth factors, and functional peptides. Many of these components are similar to those found in milk or colostrum. They act directly at the intestinal level, supporting digestion and nutrient absorption while helping reduce metabolic stress and inflammation.
  Research shows that plasma promotes a more beneficial digestive and fermentation pattern in the gut. Diets containing plasma lead to increased production of short-chain fatty acids, key compounds for intestinal health. At the same time, they reduce digestive by-products associated with intestinal stress.   Supporting the Microbiome Without Compromising Diversity
In addition, plasma modulates the microbiota gradually. It promotes bacterial populations associated with improved intestinal health while maintaining microbial diversity, which is essential for ecosystem stability.
  Importantly, this effect goes beyond digestion. The intestine acts as a systemic regulator of the body. By improving intestinal integrity and supporting mucosal immunity, the overall inflammatory load can be reduced. Consequently, improved gut health may positively influence other tissues and systems, including those involved in chronic inflammatory processes such as joints.
Scientific Evidence Applied to Pet Food
To generate specific scientific evidence for the pet food sector, APC recently supported a study focused on healthy adult dogs fed extruded diets, the most common format in dry pet food.
  The study, conducted in collaboration with the University of Illinois, was published in the Journal of Animal Science under the title:
Spray dried plasma promotes intestinal health and modulates fecal microbiota and metabolites in healthy adult dogs.
  This approach is particularly relevant because it evaluates plasma not as a corrective ingredient but as a functional component that supports balance and optimal physiological function under normal conditions.
  The conclusions are clear. Plasma inclusion:
  Promotes more efficient digestion Increases beneficial intestinal metabolites Reduces digestive by-products associated with intestinal stress Helps balance the microbiota by promoting beneficial bacteria Strengthens natural intestinal defenses without inducing inflammation Improves overall diet digestibility, with effects directly related to inclusion level
  In practice, the first visible improvements often appear in stool quality and regularity. Over time, microbiome balance contributes to greater digestive resilience and more stable immune responses.
  Rather than positioning this approach strictly in preventive clinical terms, it aligns with functional nutrition. The goal is to maintain physiological balance and reduce the risk of future imbalances.   The Future of Functional Pet Nutrition
This nutritional strategy is particularly relevant for pets with sensitive digestion, senior animals, highly active dogs, or those exposed to stress. However, the observed benefits in healthy adult dogs suggest that plasma can also form part of a long-term nutritional strategy.
  Pet nutrition is evolving. It is no longer viewed solely as nutrient supply but as a tool to support specific physiological functions.
  Looking ahead, nutrition will become increasingly personalized, evidence-based, and driven by functional ingredients acting on the gut–microbiome–immunity axis. Ingredients such as plasma, with demonstrated functionality, are redefining the future of animal nutrition.
  Innovation will not come only from new recipes. It will come from understanding how ingredients interact with animal physiology to deliver measurable, sustainable benefits over time. Source: APC

Plasma: The Functional, Natural Miracle Ingredient for Dogs and Cats!
Functional Additives

2+ MIN

Plasma: The Functional, Natural Miracle Ingredient for Dogs and Cats!

When buying pet food, treats, and supplements, modern pet parents don't just look for quality ingredients or complete and balanced nutrition. They also place emphasis on things like functional ingredients with health benefits. Plasma is a clean, natural, and highly digestible nutrient source that stands out as a functional ingredient because it benefits health and helps the planet. Learn more about plasma, how it supports whole-body health, and great products that feature it.   Plasma Supports Human Health and Pet Health
Plasma is the liquid component of blood. So when you donate blood, you're giving plasma, a life-saving gift used around the world every day to help people survive and thrive. And just like plasma supports human health, so too can it play a meaningful role in pet health and nutrition. Plasma sourced from pigs and cattle is collected and dried, preserving the amino acids, nutrients, bioactive compounds, and highly digestible proteins. It's a tasty, functional ingredient that can be added to pet foods, treats, and supplements to support vitality, well-being, and everyday health.   Adding Plasma to a Dog's or Cat's Diet Is Good for the Whole Body
Plasma about 70% to 80% protein, so you can see right away one of the main benefits for dogs and cats. Four-legged family members rely on protein-rich diets to build and repair tissues, produce enzymes and hormones, and support overall growth, function, and energy. Beyond that, plasma also contains a myriad of other beneficial compounds, including:
  Amino acids Electrolytes Minerals Antibodies Immunoglobulins Bioactive peptides Growth factors
  Together, these compounds have a systemic effect, supporting the immune system and its ability to respond to stress and inflammation. They also help with digestive health, the gut microbiome, nutrient absorption, muscle development, skin and coat health, and energy levels.
  What's more, plasma is a valuable byproduct of meat processing. Reclaiming plasma from the meat industry reduces waste, minimizes environmental impacts, and supports a more efficient food system.
  Easy Ways to Add Plasma to Your Dog's or Cat's Diet
Plasma is a powerful, natural, sustainable ingredient that supports canine and feline health at every life stage. It delivers essential nutrients, helps manage stress and inflammation, supports immunity, and promotes overall vitality, keeping dogs and cats active, resilient, and thriving. When you add food, treats, and supplements with plasma to their diet, you're supporting whole-body health for them and helping the planet too.
  Visit APC to learn more about plasma for pet health!
  Source: Animal Wellness

Baked Biscuits Utilizing Spray Dried Plasma Products
Functional Additives

2+ MIN

Baked Biscuits Utilizing Spray Dried Plasma Products

Background Information   Spray dried plasma (SDP) or Cravings (hydrolyzed plasma) are high-protein ingredients utilized in pet food for functional texture properties, enhancing palatability, or supporting overall health.   Study Objective   The study objective was to evaluate how SDP or Cravings inclusion impacts texture and palatability of baked biscuits utilizing wheat gluten.   Experimental Procedure   The study evaluated palatability and texture of baked biscuits utilizing 1% SDP or Cravings to replace wheat gluten in control formula. Palatability testing was conducted with 20 dogs for a 2-day test. Different ingredient sources and processing conditions were used in each study accounting for differences in texture of final product.
  Baked biscuits were made by preparing the dough utilizing a KitchenAid mixer equipped with a dough hook, rolling out by hand to a set depth and size, and then baking to moisture level of less than 10%. Three replicate batches of each formula were completed for analysis per study.
  Texture was measured on a TA.XT Plus utilizing an adjustable bridge with a rounded-end knife probe for a 3-point bend. Baked biscuits of 2 cm × 7 cm were placed over the two-bridge span spaced 2.5 cm apart to measure maximum force to break (hardness), fracturability, and stiffness to determine texture. Five baked biscuits per treatment were analyzed for texture from each replicate batch. Digital calipers were utilized to measure biscuit dimensions and volume.   Proof of Concept: Test Formula
    Results: Texture
 
Results: Palatability
 
Summary
SDP and Cravings can be incorporated into baked biscuits as a processing aide to impact texture depending on ingredient matrix and target, while SDP also improves palatability. Overall, both SDP and Cravings can be an alternative to vital wheat gluten to maintain or enhance product quality.
  By Joy Campbell and Angela Smith - APC
Source: All Pet Food Magazine

Beyond Dry Food: Functional Additives in the Pet Food Market
Functional Additives

5+ MIN

Beyond Dry Food: Functional Additives in the Pet Food Market

By Erika Stasieniuk

The answer is in the intersection between nutritional science, consumer behavior, and market strategy.    What Do Pet Owners Value?   The increase in pet humanization has transformed pet owners' view about food. Nowadays, they not only look for satiety but also for disease prevention, healthcare, and well-being promotion, which reflects the concern about their own nutrition and health. 
  This behavior shift is confirmed by Hobbs Jr. and Anderson (2024), who studied which healthy properties claims add value to consumers. Pet owners are willing to pay more for certain benefits, according to the authors of a study on nearly 1,600 dry dog foods.
  The statement 'allergy relief' showed a surcharge of up to 22.7%. 'Digestive health' and 'sensible skin' also correlate with more perceived value. Generic terms such as 'vitamins and minerals' or 'dental care' were associated with a lower willingness to pay, indicating that they are perceived as basic attributes rather than differentiators. This data offers a strategic orientation for the industry—clear and specific claims with visible benefits are more valuable and explain premium positioning.   Functional Additives Applications in Canine and Feline Food   Functional statements that go beyond marketing are backed up by proven efficacy ingredients.
  Additives have always been an integral part of formulations from technological and sensorial goals to nutritional and zootechnical purposes. However, its function has shifted: in fact, it has become a strategic tool for differentiation and commercial value.
  Prebiotics, natural antioxidants, essential fatty acids, and others were increasingly added to formulations both for their technical functionality and their commercial appeal. Among them, ingredients with functional effects stand out in gut health, e.g., mannan oligosaccharides (MOS), fructo-oligosaccharides (FOS), and beet pulp.
  According to Singla and Chakkaravarthi (2017), prebiotics such as inulin and FOS are non-digestible fibers serving as substrates for beneficial gut bacteria (Bifidobacterium and Lactobacillus). Classic studies highlight their benefits:
  Balance in gut microbiota (Gibson y Roberfroid, 1995). Better mineral absorption, such as calcium and magnesium (Scholz-Ahrens et al., 2007). Immune response modulation (Lomax and Calder, 2009). Reduction of inflammatory compounds in the colon (Slavin, 2013).
  MOSs are functional carbohydrates extracted from yeast cell walls, mainly from Saccharomyces cerevisiae. These compounds serve as allies in gut health as they prevent pathogenic bacteria from adhering to the mucosa. MOS are in the binding site of epithelial cells to prevent the adhesion of harmful microorganisms, a mechanism known as competitive exclusion. In addition to the protective effect, MOSs stimulate defense cells (macrophages) by exceeding mannose receptors in glycoproteins of the cell surface (Macari and Maiorka, 2000; Strickling et al., 2000).
  Beet pulp is a fermented fiber, rich in soluble and insoluble fiber. It contributes to the balance of gut microbiota, enhances fecal consistency, and improves bowel transit. Moreover, its partial fermentation in the colon generates short-chain fatty acids (SCFAs), such as butyrate, which serve as an energy source for colonocytes and contribute to the intestinal mucosa integrity (Swanson et al., 2002).
  The statements 'enhance digestive health' or 'balance of intestinal flora' are credible when included in ingredient formulations, such as inulin, FOS, MOS, and beet pulp. The connection between functionality and labeling is essential to building confidence and perception of real value.   From the Ingredient to the Positioning in the Market   Brands face the challenge of identifying technical complexity in clear, attractive, and accessible messages. 
  Instead of mentioning 'inulin' in the list of ingredients, it is better: 'natural prebiotic fiber of chicory roots that promotes gut health.'
  This approach trains the consumer and strengthens the legitimacy of the functional statement. Functional ingredients not only must be listed but also must be perceived and valued as differentiators.
  Other relevant examples:
  Omega-3 (fish oil and linseed): Related to dermis health, coat shine, and joint well-being. Vitamin E and selenium: Natural antioxidants that strengthen the immune system. Glucosamine and chondroitin: Usually present in food for senior dogs or big breeds, which support their beneficial effect in joints.   The Pillars of their Commercial Efficacy   Science-based functional ingredients with an effective dose proven by studies. Clarity and transparency in the communication of their benefits. Alignment between their value proposal and price positioning.   Opportunities in a New Scenario   The search for healthier, specific, and functional food is no longer a trend—it is the standard in the pet food market.
  In an increasingly competitive market, brands successfully combining science, formulation, and an effective communication strategy will be better positioned to address a more demanding and informed consumer.
  Prebiotics and other functional additives, when used with technical expertise and purpose, can make dry food a real tool for the health and well-being of dogs and cats. The market is open to brands that offer more than nutrition: those that build trust.
  Ideal labeling goes beyond attractive promises. It must convince consumers by presenting a science-aligned list of ingredients that support each statement. By bridging the gap between formulation and transparent communication, the industry evolves in promoting a longer and healthier life for pets.
  By Marcos Borges S. Rosa, Marcela Lobo N. Lima, and Erika Stasieniuk
Source: All Pet Food Magazine
  About the authors
Marcos Borges S. Rosa is a zootechnician with a postgraduate degree in canine and feline nutrition, and a master's in veterinary science from UFU (Federal University of Uberlândia). He offers in-person and online nutritional services for dogs and cats. Contact: www.marcosnutripet.com | Instagram: @marcosbsrr

Marcela Lobo N. Lima is a veterinarian with a postgraduate degree in canine and feline nutrition from Unyleya and works in formulation. Contact: marcela.nasc21@hotmail.com | Instagram: @marcelanasc

Erika Stasieniuk is a zootechnician with a doctorate in canine and feline nutrition from UFMG. She is the founder of SFA Consultoria and works as technical consultant in the development of pet food and ingredients. Contact: erika_stasieniuk@sfa-consultoria.com | Instagram: @erikastasieniuk
  References
Gibson, G. R., e Roberfroid, M. B. (1995). Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. The Journal of Nutrition, 125(6), 1401–1412.
Hobbs Jr., L., e Anderson, A. (2024). Assessing Price Premiums of Health and Wellness Product Attributes in Pet Food: Implications for Product Positioning and Marketing Strategies.
Lomax, A. R., e Calder, P. C. (2009). Prebiotics, immune function, infection and inflammation: a review of the evidence. British Journal of Nutrition, 101(5), 633–658.
Singla, V.; Chakkaravarthi, S. (2017). Applications of prebiotics in food industry: A review. Food Science and Technology International 23(8) 649–667. DOI: 10.1177/1082013217721769.
Macari, M.; Maiorka, A. Função gastrintestinal e seu impacto no rendimento avícola. In: CONFERÊNCIA APINCO'2000 DE CIÊNCIA E TECNOLOGIA AVÍCOLAS, 2000, Campinas.
Scholz-Ahrens, K. E., et al. (2007). Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. The Journal of Nutrition, 137(3 Suppl 2), 838S–846S.
Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417–1435.
Swanson, K. S., et al. (2002). Fruit and vegetable fiber fermentation by gut microflora from canines. Journal of Animal Science, 80(10), 2725–2734.

Understanding the Role of Antioxidants in Pet Food Preservation
Functional Additives

3+ MIN

Understanding the Role of Antioxidants in Pet Food Preservation

What Are Antioxidants and Why They Matter
An antioxidant is a molecule that protects cells from damage caused by free radicals. Antioxidants in pet food prevent fats and oils from breaking down through oxidation. Oxidation can lead to rancidity, off-flavors, reduced aroma, and the loss of essential nutrients, ultimately affecting the pet's willingness to consume the food.
  Sara explains:
  'Without proper antioxidant protection, even a well-formulated product can lose its nutritional integrity and appeal over time. Antioxidants are not just additives—they're crucial for product performance.'
  For more details on how oxidation control in pet food works, see Kemin's Oxidation Control solutions.   The Bigger Picture: Why Antioxidants Impact Palatability
Oxidation doesn't just affect nutrients—it also influences flavor, aroma, and palatability, which are critical to pets' acceptance of food. Sara notes:   'Even minor changes in flavor or smell can lead pets to reject a product. Using antioxidants correctly ensures that the food not only remains nutritious but also appetizing for cats and dogs.'
  For more on enhancing flavor and pet acceptance, explore Kemin's Palatability Solutions.   Choosing the Right Antioxidants for Your Product
Not all antioxidants are created equal, and their effectiveness depends on the type of fat used, processing methods, and storage conditions. Sara highlights that selecting the right pet food antioxidants is about understanding these interactions:
  Type of fat or oil matters: Some fats oxidize faster than others, requiring different antioxidant strategies.
  Processing conditions affect stability: Heat, moisture, and extrusion processes can impact how antioxidants perform.
  Storage and packaging are critical: Packages are exposed to a variety of conditions over their lifecycle — from heat and humidity during transport to oxygen exposure once opened by the pet owner. That's why Kemin tests antioxidants under worst-case scenarios to ensure stability and performance.
  Kemin offers tailored solutions to match these needs, including PET-OX® synthetic antioxidants for overall stability, TERMOX® ethoxyquin-free antioxidants for sensitive formulations, and NATUROX® natural antioxidants for clean-label products.   Strategies for Effective Antioxidant Use
Sara shares practical tips for incorporating antioxidants in pet food:
  Evaluate raw materials carefully: Understand the oxidative potential of fats and oils used in the recipe.
  Match antioxidants to processing methods: Choose antioxidants that maintain stability through extrusion, baking, or other manufacturing processes.
  Monitor storage and handling: Use proper packaging, limit air exposure, and educate distributors on optimal storage practices.
  Test and validate: Regularly monitor oxidation levels and sensory attributes to ensure products meet quality expectations.
  By following these strategies, manufacturers can deliver consistent, safe, and palatable products that pets enjoy while maintaining nutritional integrity.
  Pet food antioxidants are more than just additives—they are essential tools for maintaining pet food quality, safety, and palatability. By carefully selecting antioxidants, considering processing conditions, and monitoring storage, manufacturers can ensure their products remain fresh, nutritious, and appealing to pets.
  For more in-depth insights, listen to the full podcast episode with Sara Cutler below. Source: Kemin Nutrisurance