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Inflexible Formulations: What Vitamin & Amino Acid Supply Disruption Could Mean for Pet Food
 
Vitamins

3+ MIN

Inflexible Formulations: What Vitamin & Amino Acid Supply Disruption Could Mean for Pet Food  

Recent discussions around vitamin and amino acid supply chains highlight a critical issue: these nutrients are not optional in pet food. Like the animal protein sector, they are foundational to animal health, but for pet food they are also integral to product integrity and regulatory compliance. For the pet food sector, even small disruptions can have outsized impacts.   The Nutritional and Formulation Challenge
Pet food is governed by strict nutrient requirements. In the U.S., dog and cat foods must meet defined nutrient profiles that specify minimum levels of essential vitamins and amino acids per pound of product. This means formulation is not simply about substituting ingredients; it is about maintaining precise nutritional balance. When supply disruptions occur, nutritionists are forced into complex reformulation decisions, which I describe as, 'solving a Rubik's Cube' -- adjusting one component inevitably affects multiple others. 
  Ingredient shifts can alter digestion, stability and overall product performance. When key vitamins or amino acids become scarce, manufacturers may need to modify formulations, and those changes carry real risk. Nutrient imbalances may impact gut health, skin and coat quality or long-term wellness. Changes in ingredient composition can also affect palatability and food intake, which pet owners will quickly notice. At the same time, reformulations may jeopardize label claims, certifications or even patented formulations. 
  Pets, particularly cats, have unique nutritional requirements that heighten the stakes of supply disruption. Taurine, for example, is essential for cats, and inadequate levels can lead to serious health conditions such as dilated cardiomyopathy. Nutrient interactions, such as those involving thiamine and amino acid balance, can create cascading formulation challenges. Certain dog breeds also require careful amino acid fortification to avoid health complications. These sensitivities mean that even temporary shortages can have real biological consequences if not managed carefully. 
  The risks become even more pronounced in veterinary therapeutic diets, which are designed as part of a broader health management plan; for example, renal diets for kidney support. When supply disruptions force the use of alternative or endogenous nutrient sources, unintended consequences may arise, including the introduction of unwanted co-nutrients, reduced bioavailability or conflicts with the intended therapeutic outcome. In these cases, formulation changes are not just technical, they are clinical decisions with direct implications for animal health. 
  Alternative ingredient strategies often rely on endogenous sources or complex co-products. While these can help bridge supply gaps, they introduce new uncertainties around nutrient availability, digestibility and additional nutrients that must be managed. In pet food, even small ingredient swaps can significantly alter the overall formula, increasing the risk to product design and performance.    A Supply Chain Issue with System-Wide Implications
One of the most important realities is that pet food does not operate in isolation. The same supply chains that support livestock production and human nutrition also supply companion animal diets. 
  As a result, disruptions in vitamin and amino acid production affect multiple sectors simultaneously. Increased costs or limited availability upstream in protein production ultimately translate into higher costs and tighter constraints downstream in pet food. This interconnectedness underscores a broader point: pet food is part of a larger food security system in North America. 
  While rising costs are a concern, the more fundamental challenge is maintaining supply stability. Pet food formulations are not easily or frequently changed due to regulatory requirements, labeling and packaging constraints, product claims and certifications and intellectual property considerations. Because of these constraints, the industry cannot simply adjust on the fly. Stability in ingredient supply is essential to maintaining consistent, safe and compliant products. 
  Ensuring a stable supply of vitamins and amino acids is critical to the future of the pet food industry. This will require coordinated efforts across agriculture, ingredient manufacturing and regulatory systems. Without that stability, the industry faces increasing pressure on formulation integrity, product performance and ultimately animal health. 
  The question is not just how to respond to disruption, but how to build a more resilient supply chain that supports pets, producers, and consumers alike.  Source: IFEEDER

Symrise Invests in Bond Pet Foods to Accelerate Sustainable Innovation in Pet Nutrition Via Precision Fermentation
 
Proteins

2+ MIN

Symrise Invests in Bond Pet Foods to Accelerate Sustainable Innovation in Pet Nutrition Via Precision Fermentation  

Symrise today announced a strategic equity investment in Bond Pet Foods, a U.S.-based biotechnology company that uses precision fermentation to produce animal-identical proteins complementing the existing pet food portfolio of Symrise. The partnership supports Symrise's ambition to develop biotech-enabled ingredients that work better for pets and the planet, strengthening the long-term competitiveness and sustainability leadership of Symrise Pet Food.
  With this partnership, Symrise will leverage Bond Pet Foods' technology to help address key industry challenges, including supply-chain continuity and growing consumer demand for sustainable products that diversify the source of pet food ingredients. For pet food manufacturers, the collaboration aims to broaden access to high-quality proteins while supporting resilience and responsible sourcing.
  'This investment marks an important step in advancing our strategy to develop next-generation sustainable ingredients with biotechnology. By combining Bond's fermentation capabilities with Symrise's application expertise and market insight, we can deliver high-performance nutrition solutions and create new growth opportunities for our customers,' said Diego Maurizio, General Manager, Palatability & Nutrition Business Line at Symrise.
  Founded in 2017, Bond Pet Foods develops animal-identical proteins for pet nutrition using precision fermentation. The company has progressed its platform through several development agreements, building expertise in bringing novel protein ingredients toward real-world application.
  'We have put great effort into building a new way to produce animal-identical proteins for pet food applications. Now, we find it exciting to see that work gaining traction across the industry", said Rich Kelleman, CEO of Bond Pet Foods. "Partnering with Symrise marks an important step forward bringing their deep expertise in pet nutrition and taste to further expand how our ingredients perform and can be used by pet food manufacturers,'
  "This investment advances our ambition to scale biotechnology across our business. With this, we aim at effectively supporting long-term resilience, portfolio diversification, and a stronger innovation pipeline", says Walter Ribeiro, President Taste, Nutrition & Health at Symrise. "By helping our customers develop more sustainable pet food formulations, the collaboration reinforces Symrise's sustainability commitments and consumer-driven innovation strategy." Source: Symrise AG
About Bond Pet Foods Bond Pet Foods is a Boulder, Colorado-based company using precision fermentation to produce animal-identical proteins for the pet food industry. By combining yeast fermentation with food science, Bond creates high-quality animal-identical proteins that meet the nutritional needs of dogs and cats, while supporting a more sustainable and resilient food system.
  Bond supplies these ingredients to pet food manufacturers for use in food, treat, and supplement applications.
  The company's investors include leading funds and organizations across the biotechnology, ingredient, and pet nutrition sectors, including Genoa Ventures, Lever VC, ADM Ventures, Cavallo Ventures (Wilbur-Ellis), Agronomics, Thia Ventures, KBW Ventures, iSelect Fund, Stage 1 Fund, Plug and Play Ventures and Symrise North America. www.bondpets.com

New Research: Plasma Positively Impacts Mobility-Related Outcomes in Adult Dogs
Other microingredients

2+ MIN

New Research: Plasma Positively Impacts Mobility-Related Outcomes in Adult Dogs

Ankeny, Iowa, USA – March 18, 2026 –> Understanding how nutrition influences mobility, inflammation, and joint-associated biomarkers continues to be an important area of focus in companion animal nutrition. A new study published in the Journal of Animal Science, based on collaborative research between APC and China Agricultural University, evaluated the inclusion of plasma in extruded diets for senior dogs experiencing mobility challenges.
  This work is part of APC's broader research initiative exploring the connections between nutrition, gastrointestinal health, systemic biomarkers, and healthy aging in companion animals.
  Mobility and joint health remain two of the most sought-after functional areas in pet nutrition. In this 42-day study, senior dogs with mobility challenges were evaluated across multiple endpoints, including lameness scoring, diet digestibility, and select serum and synovial fluid biomarkers associated with immune signaling, oxidative capacity and joint health. Differences were observed between dietary groups across several measured outcomes, including mobility assessments and select biomarker responses.
  Key findings included:
  Mobility assessments: Improved lameness scores compared to control diets over the study period.
  Inflammatory markers: Favorable changes in select cytokine-related biomarkers associated with immune signaling.
  Joint-related biomarkers: Improvements in metalloproteinase activity and other joint-associated measures evaluated in serum and synovial fluid.
  Digestibility: Crude protein digestibility was improved, confirming nutritional performance of the diet.
'These findings add to the growing body of research evaluating how functional plasma proteins may support mobility-related outcomes, overall health, and longevity in adult dogs,' said Jerry Frankl, President and CEO of APC. 'We remain committed to collaborating with leading research institutions and advancing science-based nutrition strategies that promote healthy aging and long-term vitality in companion animals.'
  To read the full study: https://academic.oup.com/jas/article/doi/10.1093/jas/skag043/8487757 Source: APC

A to Z of Pet Food: Proteins 
 
Proteins

2+ MIN

A to Z of Pet Food: Proteins   

Made up of amino acids, proteins build and maintain structures in the body and help support muscles, bones, blood, organs and skin and coat health. Because dogs and cats can't synthesize all the essential amino acids they need, these nutrients must come from complete and balanced pet food.     Sources of Protein    Proteins are commonly classified into two large categories based on their source: animal-based and plant-based.  
  Animal-based protein includes chicken, beef, turkey, lamb and fish.  Plant-based protein includes ingredients like soybeans, corn and lentils. 
  While animal protein sources have higher amounts of essential amino acids, dogs can still thrive on a well-formulated plant-based diet. Cats, on the other hand, are obligate carnivores and rely on animal-based protein for specific amino acids, like taurine, methionine and cystine.    How Much Protein Does My Pet Need?    The Association of American Feed Control Officials (AAFCO) has set the following minimum protein requirements for pet food: 
  Dogs   Adult: ≥ 18% crude protein  Puppy: ≥ 22% crude protein  Cats   Adult: ≥ 26% crude protein   Kitten: ≥ 30% crude protein 
  Puppies and kittens require a higher amount of protein in their diet to support growth and development. Additionally, cats need more protein than dogs and have more specific amino acid requirements. 
  Protein is an essential nutrient for dogs and cats, and diets containing more than the minimum required amount of protein are often beneficial. In fact, in obese dogs, high-protein, low-carb diets can promote both proper body condition and steadier blood glucose levels. Additionally, studies suggest that aging pets likely have a higher dietary protein requirement than younger pets.   
  That said, extremely high levels of protein, especially when not balanced with other nutrients, may pose health risks, such as disrupting a pet's calcium to phosphorus ratio or contributing to weight gain. Consult with your veterinarian to ensure your pet's protein intake matches their unique needs, including life stage, size and activity level.    Looking Ahead: Emerging Protein Alternatives    Did you know over 93% of pet food products worldwide contain animal protein? Although these are most often responsibly sourced as by-products, as the global population grows, so will the demand for animal protein—raising concerns about demand outpacing supply. 
  To ensure the long-term sustainability of pet food, industry research has turned toward alternative sources of protein, including insect-based ingredients, invasive species (such as Asian carp and blue catfish) and single-cell ingredients (like algae, fungi and yeast).  
  Another alternative protein source includes meat products not commonly consumed by humans, like alligator, kangaroo and rabbit. While these alternative ingredients are still being evaluated, they could play a key role in supporting a pet's complete and balanced diet in a more sustainable way.  Source: Pet Food Institute

Gut Helath: What Does Science Say About the Microbiome and the Role of Plasma in Pets?
Other microingredients

4+ MIN

Gut Helath: What Does Science Say About the Microbiome and the Role of Plasma in Pets?

Today, the intestine is recognized as a key axis connecting digestion, immunity, and overall well-being. As a result, the microbiome has become one of the main drivers of innovation in animal nutrition.
  At APC, this focus on gut health is not a recent trend but rather the natural evolution of decades of research in nutrition. The company specializes in functional ingredients for animal nutrition and began its work with plasma-derived functional proteins in livestock production, where the link between gut integrity, immunity, and performance is well documented. Over time, this expertise has been transferred to the pet food sector, where the microbiome is now understood as a crucial factor in improving quality of life for dogs and cats, even in apparently healthy animals.
  The intestinal microbiome plays a key role in digestive, immune, and metabolic health, directly impacting overall well-being.  
The Gut: A Key Ecosystem for Whole-Body Health
The gut is not just a digestive organ. It is a complex ecosystem where nutrients, microbiota, and the immune system interact continuously. A significant portion of the body's immune defenses is located in the intestine. Therefore, any imbalance in the microbiota can have effects that extend well beyond digestion.
  Disruptions in this ecosystem are associated with recurring digestive disorders, poor stool quality, or food intolerances. Moreover, they are linked to inflammatory processes that may affect skin condition, immune responsiveness, and overall metabolism. Increasing scientific evidence confirms that maintaining a balanced microbiome is essential for long-term systemic stability.   Plasma: A Functional Protein with Benefits Beyond Nutrition
Within this context, plasma has established itself as a high-value functional ingredient. It is a nutrient-dense protein obtained from surplus blood collected at facilities approved for human consumption. Through a carefully controlled spray dried process, its functional components are preserved.
  Unlike many conventional protein sources used in pet nutrition, plasma provides not only amino acids but also bioactive compounds such as immunoglobulins, growth factors, and functional peptides. Many of these components are similar to those found in milk or colostrum. They act directly at the intestinal level, supporting digestion and nutrient absorption while helping reduce metabolic stress and inflammation.
  Research shows that plasma promotes a more beneficial digestive and fermentation pattern in the gut. Diets containing plasma lead to increased production of short-chain fatty acids, key compounds for intestinal health. At the same time, they reduce digestive by-products associated with intestinal stress.   Supporting the Microbiome Without Compromising Diversity
In addition, plasma modulates the microbiota gradually. It promotes bacterial populations associated with improved intestinal health while maintaining microbial diversity, which is essential for ecosystem stability.
  Importantly, this effect goes beyond digestion. The intestine acts as a systemic regulator of the body. By improving intestinal integrity and supporting mucosal immunity, the overall inflammatory load can be reduced. Consequently, improved gut health may positively influence other tissues and systems, including those involved in chronic inflammatory processes such as joints.
Scientific Evidence Applied to Pet Food
To generate specific scientific evidence for the pet food sector, APC recently supported a study focused on healthy adult dogs fed extruded diets, the most common format in dry pet food.
  The study, conducted in collaboration with the University of Illinois, was published in the Journal of Animal Science under the title:
Spray dried plasma promotes intestinal health and modulates fecal microbiota and metabolites in healthy adult dogs.
  This approach is particularly relevant because it evaluates plasma not as a corrective ingredient but as a functional component that supports balance and optimal physiological function under normal conditions.
  The conclusions are clear. Plasma inclusion:
  Promotes more efficient digestion Increases beneficial intestinal metabolites Reduces digestive by-products associated with intestinal stress Helps balance the microbiota by promoting beneficial bacteria Strengthens natural intestinal defenses without inducing inflammation Improves overall diet digestibility, with effects directly related to inclusion level
  In practice, the first visible improvements often appear in stool quality and regularity. Over time, microbiome balance contributes to greater digestive resilience and more stable immune responses.
  Rather than positioning this approach strictly in preventive clinical terms, it aligns with functional nutrition. The goal is to maintain physiological balance and reduce the risk of future imbalances.   The Future of Functional Pet Nutrition
This nutritional strategy is particularly relevant for pets with sensitive digestion, senior animals, highly active dogs, or those exposed to stress. However, the observed benefits in healthy adult dogs suggest that plasma can also form part of a long-term nutritional strategy.
  Pet nutrition is evolving. It is no longer viewed solely as nutrient supply but as a tool to support specific physiological functions.
  Looking ahead, nutrition will become increasingly personalized, evidence-based, and driven by functional ingredients acting on the gut–microbiome–immunity axis. Ingredients such as plasma, with demonstrated functionality, are redefining the future of animal nutrition.
  Innovation will not come only from new recipes. It will come from understanding how ingredients interact with animal physiology to deliver measurable, sustainable benefits over time. Source: APC


Proteins

Proteins Unlock Innovative Possibilities in Wet Pet Food Formulation with the Power of Faba Bean Protein

4+ MIN

Unlock Innovative Possibilities in Wet Pet Food Formulation with the Power of Faba Bean Protein

Demand for wet pet food is on the rise, with the segment's growth being driven by pet owners looking for premium and nutritionally balanced pet food with good palatability.i At the same time, consumers increasingly want to see more plant-based offerings that also reflect their own sustainability values. In response to these evolving expectations, BENEO has conducted a new set of technical trials to explore the potential of its faba bean protein concentrate as a functional, plant-based ingredient for wet pet food.
Exploring Alternatives to Animal Blood Plasma
In premium and super-premium wet pet food, maintaining consistent product quality is essential. These products typically contain at least 50 wt% total moisture, and their quality is standardised and maintained through the addition of spray-dried animal blood plasma (ABP). This ingredient provides excellent texturizing and emulsifying properties but can come at a high cost. Moreover, due to its animal origin, ABP is increasingly perceived as undesirable by consumers who increasingly want more plant-based ingredient options for their pets.
  To address these challenges, BENEO initiated a series of technical trials in collaboration with Passion4Food, a specialist service provider for the pet food industry. The objective was to evaluate whether faba bean protein concentrate could be used as a suitable and cost-effective alternative to ABP in wet pet food formulations.
Technical Trials Confirm Strong Functional Performance
The initial trials investigated the performance of BENEO's faba bean protein concentrate when partially (50%) or fully (100%) replacing ABP in high-protein wet pet food loaves (paté format). The results showed that the ingredient could be successfully used for both full and partial ABP replacement, with no significant change in the end product's weight or texture. This means producers can maintain desired product quality while achieving considerable cost savings compared to ABP. Based on these promising results, BENEO carried out follow-up trials using a test recipe suitable for commercial scalability.  

As part of the following additional trials, the same percentages of ABP and faba bean protein concentrate were used and compared to a test recipe in which ABP was partially replaced at 50% with pea protein concentrate.
  The data demonstrated that BENEO's faba bean protein concentrate acted as an excellent and cost-effective alternative binder to ABP, with no significant changes observed in loaf height, weight, hardness, or adhesiveness. In contrast, the partial replacement of ABP with pea protein concentrate led to a significant decrease in hardness, indicating that faba bean protein concentrate provides a higher binding capacity in wet pet food loaves. This makes it a valuable ingredient for maintaining the desired texture of the end-product while reducing reliance on animal-derived binders.  
Patent Application Supports Scientific Innovation
Following these successful results, BENEO filed an international patent application for the use of faba bean protein concentrate as an alternative to spray-dried animal blood plasma in wet pet food. The patent application was published in August 2025, underscoring BENEO's dedication to research-based innovation and functional ingredient development for the pet food industry.
Nutritional and Formulation Advantages
Beyond its technical and cost benefits, BENEO's faba bean protein concentrate also provides strong nutritional value. With a protein content of 61 g per 100 g on a dry matter basis and an ileal digestibility score of almost 90%, it is a highly digestible source of protein. Its amino acid profile is relatively rich in lysine and can complement cereal proteins, such as rice protein or vital wheat gluten, to achieve a complete essential amino acids profile.

The ingredient also provides flexibility for product positioning. It is listed in the EU Catalogue of Feed Materialsii and can be used in formulations that carry 'no grain' claims.
Contributing to Sustainable and Locally Sourced Solutions
Sustainability has become an increasingly important consideration for both consumers and producers. BENEO's faba bean protein concentrate offers strong sustainability credentials linked to the faba bean crop and to BENEO's local sourcing and production processes in Germany. Local production in the new state-of-the-art pulse-processing plant, located in Obrigheim, further supports short transport distances, secures supply and reduces the environmental impact compared to more resource-intensive ingredients.
  Dr Maygane Ronsmans, Product Manager Animal Nutrition at BENEO, comments:

'With two in three pet owners considering plant-based proteins to be better for the environmentiii, demand has grown for sustainable and locally sourced vegetal protein ingredients. As the technical trials show, BENEO's faba bean protein concentrate offers pet food manufacturers a win-win scenario: producers can decrease their recipe costs while benefitting from secure supply and meeting consumer expectations for more sustainable and plant-based pet foods, without impacting the quality of the end-product.'
Supporting the Next Generation of Wet Pet Food Innovation
The findings from BENEO's trials confirm that faba bean protein concentrate combines functionality, nutritional quality and sustainability. It performs effectively as a binder in wet pet food, delivers a high level of digestible protein, and provides a viable alternative to animal blood plasma in applications where consistency and texture are key.
  For pet food manufacturers, this opens the door to new formulation strategies that balance technical performance, cost efficiency and environmental responsibility. As the market continues to evolve, ingredients such as BENEO's faba bean protein concentrate can help producers meet consumer expectations for more plant-based, locally sourced and high-quality products.
  Interested in learning more about BENEO's ingredient solutions? Find more details here  By BENEO
Source: All Pet Food Magazine References
i Wet Pet Food Market Analysis - Size, Share, and Forecast Outlook 2025 to 2035, Future Market Insights Inc, 2024. 
ii Commission Regulation (EU) No 68/2013 of 16 January 2013 on the Catalogue of feed materials – Faba bean protein concentrate is listed under entry 3.7.5: 'Horse bean protein' 
iii BENEO Consumer Research On Pet Care 2025. FMCG Gurus conducted a quantitative online survey in 2025 with 2.500 pet owners in the US, Brazil, UK, Germany, and China (250 cat and 250 dog owners per country).

Other microingredients <strong>Colmax</strong>: Natural Choline for Neural, Metabolic, and Digestive Well-being in Pets

3+ MIN

Colmax: Natural Choline for Neural, Metabolic, and Digestive Well-being in Pets

In companion animal nutrition, well-being begins long before food reaches the bowl. Ingredient quality and nutrient balance are key factors in sustaining the vitality and metabolic health of dogs and cats.

Among these nutrients, choline plays a fundamental role. Its presence in the diet contributes to proper liver function, lipid transport, and the development of the nervous system. Dogs and cats do not synthesize sufficient amounts on their own, making the inclusion of this ingredient essential.

Colmax is a natural source of choline and inositol developed by Adinnova to help regulate liver, lipid, and energy metabolism. Its plant-based formulation enables this essential nutrient to be incorporated into different pet food formulations in a stable and safe manner.  
Why Is Choline Key in Pet Nutrition?
Choline is involved in fundamental physiological processes, particularly liver metabolism, fat transport, and nervous system function. When dietary intake is insufficient, liver disorders, reduced vitality, or muscle weakness may occur.

Traditionally, the most widely used source of choline in animal nutrition has been choline chloride. However, this molecule presents certain technological limitations. It is a hygroscopic and reactive compound that can interact with other dietary ingredients, affecting the stability of sensitive nutrients during feed processing and storage. Among the most common effects are the oxidation of vitamins, pigments, and amino acids. Moreover, its origin is associated with petrochemical byproducts.

Natural sources of choline represent an alternative aimed at overcoming these limitations. Plant-based choline is associated with phospholipids such as phosphatidylcholine, which are in the cellular membrane structure and contribute to its biological stability.
Adinnova's Natural Choline
Adinnova's source of choline and inositol, Colmax, was developed to contribute to metabolic balance in animal nutrition. Its formulation combines plant-based choline with functional compounds that support cellular performance.

Its components include phospholipids, such as phosphatidylcholine and phosphatidylinositol, as well as coadjuvants, for example, butyric acid and plant extracts, that support intestinal and liver health and nutrient absorption. This combination helps optimize lipid transport and utilization, helping metabolic balance and pet vitality through nutrition.

Another relevant characteristic is its technological stability. Colmax is a fluid, non-hygroscopic presentation that withstands the thermal treatments commonly used in pet food processing, as these molecules remain active and maintain absorption capacity. In turn, its use allows lower inclusion levels in the formula compared with synthetic choline sources, optimizing formulation efficiency and economic performance.
The Impact of Colmax in Pet Care
Colmax provides choline, a pseudovitamin that dogs and cats do not synthesize in sufficient amounts. Its presence in the diet helps reinforce the integrity of cell membranes and participate in neurometabolic processes linked to vitality and normal body function.

This nutritional additive supports the healthy development of the brain, heart, liver, muscles, and nervous system, contributing to the overall well-being of animals through nutrition.

Its stable formulation also allows easy incorporation into pet food. The recommended dosage in pet care ranges from 150 to 500 g/ton of feed, and it can replace choline chloride (60%) at an approximate ratio of 1-4, optimizing the use of space in the diet.

By supporting cellular function, Colmax helps sustain the vitality and well-being of dogs and cats throughout all life stages. Its nutritional contribution reinforces cell membrane integrity, supports neuronal development, and contributes to pets' overall health.
Studies on Colmax
This biosolution has been supported by scientific evaluations aimed at understanding its effect on animal metabolism. During 2024 and 2025, Adinnova carried out studies in collaboration with the National Institute of Agricultural Technology (INTA) to analyze productive, metabolic, and physiological parameters, including performance, liver function, and tissue analysis. The results validated the contribution of Colmax as a nutritional additive that supports the general well-being of animals.  
Gene expression studies were also conducted using advanced sequencing technologies to observe how the organism responds to its inclusion in the diet. Analyses have shown that Colmax modulates several metabolic pathways linked to nutrient utilization and cellular energy production.

Lower activation of genes associated with cell proliferation processes was observed. When dysregulated, these mechanisms are often linked to different pathologies, including tumor processes such as cancer. In other words, Colmax supports an active and balanced metabolism without stimulating cellular mechanisms associated with uncontrolled proliferation. By Adinnova
Source: All Pet Food Magazine

About Adinnova
Adinnova is an Argentine company, present in international markets, dedicated to the development of natural additives for animal nutrition. Each biosolution integrates science and innovation applied to wellbeing and productivity.

More information on our website: adinnova.com.ar
 


Pulses and Oilseeds

Pulses and Oilseeds Grain-Free Pet Food for Cats and Dogs
 

4+ MIN

Grain-Free Pet Food for Cats and Dogs  

WHAT ARE 'GRAIN-FREE' PET FOODS?
Pet foods that are sold as 'grain-free' typically do not contain grains. Grain-free foods typically contain ingredients such as pulses including beans, chickpeas, and lentils, and can also include tubers (e.g., potatoes). More recently, grain free pet foods have become a popular feeding choice for some pet owners.
  WHAT ARE GRAINS?
Grains (cereals) are a group of ingredients that contain mainly starch as well as varying amounts of protein, fibre, lipids, vitamins, and minerals and are used in pet foods. Grain examples include rice, corn, wheat, barley, sorghum and oats.   WHAT ARE PULSES?
Pulses are defined as the dried edible seeds of plants in the legume family1. Examples of pulses include dried beans, broad beans/faba beans, peas, chickpeas/garbanzo beans, and lentils. Pulses contain starch (typically at levels lower than cereals) as well as protein (at levels higher than cereals), fibre and some lipids, vitamins and minerals.   DOES 'GRAIN-FREE' MEAN CARBOHYDRATE FREE?
Carbohydrates, which include starches and fibres, are an important source of energy and promote digestive health. Carbohydrates are present in ingredients typically found in 'grain-free' recipes for instance in pulses (e.g., beans, chickpeas, lentils, etc.), potatoes, and sweet potatoes.

Starch plays a crucial role in the manufacture of dry pet food. For more information about the role of carbohydrates in pet food see the FEDIAF factsheet on carbohydrates2.
  WHAT IS GLUTEN AND WHERE DO YOU FIND IT?
Gluten is a type of protein. It is found in some cereal grains (wheat, barley, and rye). Gluten can be used to bind items together, such as in bread. Gluten is composed of two main proteins – glutenin and gliadin, with gliadin making up 70% of the protein content. Wheat gluten intolerance is very rare in dogs and has not been reported in cats. It is recommended to consult with your veterinarian if you think your pet could benefit from a gluten-free diet. There are many ingredients commonly believed to contain gluten that are actually gluten-free, including quinoa, buckwheat, rice, millet, and maize (corn).   ARE 'GRAIN-FREE' PET FOODS HEALTHIER?
The most important consideration when deciding what diet to feed is whether it provides complete and balanced nutrition. If there is too much of one nutrient and not enough of others, it will impact the pet's health. This principle is true regardless of whether the pet food contains grain or not.
  The best way to ensure a healthy diet is to feed a complete food appropriate to the pet and their life stage. Your veterinary health care team can help select an adequate food for each case. For those that prefer grain-free pet food, there is a good selection of products on the market.   ARE 'GRAIN-FREE' DIETS BETTER FOR PETS WITH ALLERGIES?
While adverse reactions to food do occur in pets, the true prevalence of dietary intolerance or allergy in pets is unknown but thought to be rare. Reports vary, however one review found that cutaneous adverse food reactions (CAFR) – which include allergies as well as intolerances – have a prevalence of between 1-2% of dogs and 0.2% of cats, presented to veterinarians3. It is important to remember that not all allergies are linked to food e.g., fleabite allergy, and it is important to investigate all potential causes with your veterinarian.
  Whilst a very small number of pets, like humans, may be intolerant or allergic to a particular grain, this does not mean that other grains are not tolerated, that all pets will be affected, or that any one grain is inherently bad for the health of pets.
  Available research has highlighted that the most common proven allergens for cats and dogs are protein sources and include beef, chicken, fish, and dairy products4. Owners concerned about dietary intolerances or allergies should always speak to their veterinarian. It is important to work closely with your veterinarian to determine the cause of your pet's allergy. An allergic response can occur to any protein, including those contained in cereals and pulses. Specialized diets are available that are designed for the reduction of food intolerances and allergies.   ARE 'GRAIN-FREE' DIETS LINKED TO HEART PROBLEMS IN DOGS?
The US Food and Drug Administration (FDA) opened an investigation into the occurrence of non-hereditary dilated cardiomyopathy (DCM) in dogs in 2018, when they noted an association between reported cases of DCM and some diets containing a very high proportion of pulses and/or potatoes5,6. Diets reported included both 'grain-free' and grain-containing formulations. In some cases of DCM, a change in diet is part of the treatment as it can result in clinical improvement. Research to examine a potential cause has been inconclusive to date.
  The FDA is also continuing to explore the role of genetics, underlying medical conditions, and/or other factors in DCM. The FDA did not recall any products at any time. In December 2022, FDA issued a statement saying that it does not intend to release further public updates on DCM and diets until there is meaningful new scientific information to share.
  If you have any questions relating to DCM it is recommended that you talk to your veterinarian. Source: FEDIAF
  References
Ingredient Definitions | IPIC – International Pulse Ingredient Consortium (pulseingredients.com). ↩︎
Carbohydrates in dog and cat food | FEDIAF (europeanpetfood.org) ↩︎
Olivry T, Mueller RS. Critically appraised topic on adverse food reactions of companion animals (3): prevalence of cutaneous adverse food reactions in dogs and cats. BMC Vet Res. 2017 Feb;13(1):51. doi: 10.1186/s12917-017-0973-z. PMID: 28202060; PMCID: PMC5311844. ↩︎
Mueller RS, Olivry T, Prélaud P. Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats. BMC Vet Res. 2016 Jan 12;12:9. doi: 10.1186/s12917-016-0633-8. PMID: 26753610; PMCID: PMC4710035. ↩︎
FDA Investigation into Potential Link between Certain Diets and Canine Dilated Cardiomyopathy | FDA ↩︎
Questions & Answers: FDA's Work on Potential Causes of Non-Hereditary DCM in Dogs | FDA ↩︎

Formulation Holistic Stability with Functional Ingredients and Real Value

5+ MIN

Holistic Stability with Functional Ingredients and Real Value

3A BIOTECH and Real Value: You Don't Buy It, You Protect It
The value of a raw material is not defined only by its specification sheet, but by its ability to remain stable over time. Pet food is a living system, exposed to chemical changes, sensory alterations and microbiological hazards during processing, storage and transport—and finally when the pack is opened at home. Throughout that journey, stability determines whether the formulation delivers on its promise.

How to Prevent Loss of Real Value    
Fats and oils, meals and proteins are core pillars of metabolisable energy, palatability and the supply of essential nutrients. At the same time, they are the components most vulnerable to degradation. Lipid oxidation generates free radicals and peroxides that damage vitamins and other fat-soluble compounds, alter aroma and reduce the food's actual bioavailability. These processes begin as soon as the raw material is exposed to air and continue throughout the entire shelf life.

The consequences are direct: a drop in real energy delivery, loss of palatability, the formation of undesirable secondary compounds and reduced aroma stability. In practice, the lipid profile the animal consumes may no longer match what is declared. That is why oxidative stability is a central parameter of real value: if an ingredient oxidises easily, its nutritional and functional value diminishes long before it reaches the consumer.

Moreover, oxidation is not only a sensory issue. Certain compounds derived from rancidity can contribute to digestive imbalances. In pet food—where tolerance and the microbiome matter—protecting against oxidation also protects the nutritional experience.
3A BIOTECH and Microbiological Safety: The Other Pillar of Real Value
Alongside oxidative loss comes microbiological instability. Animal-origin raw materials and certain cereals can promote the growth of moulds and bacteria if not properly controlled. The challenge is compounded by the potential presence of heat-stable mycotoxins, which can survive processing and compromise final product safety.

Even moderate microbial loads can accelerate degradation and shorten shelf life in ways that are not immediately visible. For that reason, microbiological quality is a critical component of real value: it determines safety, stability and formulation performance, and it also influences batch-to-batch consistency.

Beyond Price: Technological Efficiency and Functional Value 
In a market that has historically competed in cost, more and more manufacturers recognise that differentiation is not only about purchase price, but about true functional value: what an ingredient delivers, what it preserves, and what it guarantees. Evaluation moves beyond '€/tonne' and starts to include stability, digestibility, control of wastage, sensory consistency and fewer issues/complaints.

This evolution reflects a more demanding end consumer seeking premium, natural products with tangible benefits. It also pushes the industry towards integrated systems that not only protect raw materials but also provide technological and biological functionality.
3A BIOTECH Functional Ingredients: Protect, Complement, Optimise
A functional ingredient—typically natural in origin, derived from plants, microorganisms or bioactive extracts—provides additional benefits either to the organism or to the formulation itself. In pet food, this translates into improvements, such as gut-health support, immune reinforcement, oxidative stabilisation, microbiota modulation, cellular protection against oxidative stress, and improved digestibility.

From a technological perspective, functional ingredients extend product stability, preserve organoleptic integrity and reduce degradation during storage. They can also help optimise texture, stabilise emulsions, minimise unwanted reactions and support preservation, by reducing variability and enabling more consistent nutritional claims.
Holistic Stability with 3A BIOTECH: Antioxidants + Preservatives, By Design
To preserve real value, the industry relies on carefully designed antioxidant and preservative systems. Antioxidants work by preventing free-radical formation and protecting lipid integrity. In parallel, preservatives based on organic acids help keep microbial loads under control, avoiding deterioration that would reduce the initial nutritional value.

When these systems are formulated with an integrated approach—synergy, correct dosing and process compatibility—they stop being 'additives' and become functional ingredients: they influence stability, safety and overall formula performance.
3A BIOTECH in Dry and Wet: Two Challenges, One Goal
In dry foods, the risk of rancidity increases when oxidation-susceptible meals are combined with oils applied as coatings. Processing and storage time can intensify degradation, affecting aroma, flavour and acceptance by the animal.

In wet foods, although wax coatings can help minimise drying out—particularly relevant for cats due to their more fragmented feeding pattern—it remains essential to stabilise emulsions and control oxidative and microbiological degradation. Here, emulsion physical stability is key to maintaining texture, appearance and palatability: small variations can trigger defects visible to the consumer.
3A BIOTECH TOCOTYROSOL: Stability + Functionality in One Solution
A balanced combination of antioxidant protection and functional support is found in formulations such as TOCOTYROSOL by 3A BIOTECH. This solution is developed using natural antioxidants—tocopherols and extracts of rosemary, olive and green tea—and is designed to integrate efficiently into manufacturing processes for both dry and wet foods.

Its antioxidant synergy helps preserve sensory and nutritional stability from production through to consumption, supporting lipid profile integrity, palatability and product consistency. In addition, it incorporates a prebiotic angle that supports the intestinal microbiota and digestive efficiency, aligning with the growing demand for more functional formulations.

From the manufacturer's perspective, these solutions deliver value at the technological stage (oxidation control, stability, preservation and reduced variability) and help sustain formulation performance over time. In other words, they enable the final product to fulfil the brand promise—batch after batch.
Conclusion: Raw Material, Real Value
The pet food industry no longer competes to be the cheapest, but to be the most efficient, stable and functional. In a sector where every ingredient is an investment, ensuring raw materials retain their real value is a strategic decision: it improves final quality, reduces issues and strengthens consumer trust.

At 3A BIOTECH, we help brands protect that value with natural solutions based on functional ingredients and holistic stability systems. 

Would you like to validate it on your own line? Request a technical assessment or a pilot trial with TOCOTYROSOL and see how well-designed protection can translate into greater stability, a better consumption experience and a more consistent product. By 3A BIOTECH
Source: All Pet Food Magazine

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